Cours : Pharmaceutic process

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Institute: Science and Technology
Department: Process Engineering (PE)
Target public: Third year PE
Fields of Specialization: Polymers
Course title: Pharmaceutical Processes
Credit: 1
Coefficient: 1
Duration: 15 weeks
Weekly timetable: 1h 30 min of course
Place of teaching: Classroom 3
Teacher: MAYOUF Imane
Contact: mayouf.i@centre-univ-mila.dz
Evaluation methods: A final exam 100%
Responses by e-mail: Do not hesitate to contact me I will respond as soon as possible.
Teaching objectives Chat
1- Introducing the basic notions on therapeutic molecule synthesis, treatment, purification, and formulation;
2- Developing the manufacturing of therapeutic medicines like the synthesis of active pharmaceutical ingredients (APIs);
3- Knowledge of the methode of API synthesis;
4- Analyse the properties of the obtained ''galenic formulation'' ;
5- Analyze the synthesis processes, treatment, and purification of therapeutic molecules;
6- Evaluate the strengths and weaknesses of different galenic formulations and their impact on therapeutic efficacy.

Prerequisites

In order to fully understand this course, the student must have:

- Prior knowledge of the basic concepts of general chemistry: chemical bonds, atoms, molecules, etc.

- Prior knowledge of the basic concepts of organic chemistry: nomenclatures, steriochemistry, elimination reactions, substitute reactions, solvation, preparation of molecules, etc.

- Preliminary notions on conventional extraction methods;

Direct Chat

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Hello Dear students;
I'll wait for you every week after the course to answer your questions and to enrich the discussions

Detailed contents

This course is devided into four chapters, as represented in the mental map

Chapter 1: The medicine

• Introduction

• Definitions

• The stages of drug development

• Different classifications of drugs

• Active ingredients

• Excipients

• The conditioning

• Drug activity and toxicity

• Become active ingredients in the body

Chapter 2: synthesis operations

• Sources of active ingredients

• Methods for obtaining natural substances

• Synthetic methods

• Biotechnological methods

Chapter 3: Preformulation

• Routes of administration

• Choice of dosage forms

• Biopharmaceutical classification (solubility, permeability)

• Dissociation coefficient, partition coefficient

Chapter 4: Manufacturing Environment

• Pharmaceutical company

• Manufacturing of pharmaceutical water

• Air treatment

• Concept of quality in the pharmaceutical industry

Pharmaceutic process

Aperçu des sections

Généralités

Prerequisites

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Detailed contents

Chapter 1: Drugs/medicine

Chapter 2: Synthesis operations

Chapter 3: Preformulation

Chapter 4: Pharmaceutical companies